Using icons in RTL development can be tricky. Keep in mind that some of them might have to be mirrored, and some could be considered offensive to people of some nationalities, so double-check that the icons you’re using make sense.
Icons that are symmetrical and that don’t point in a particular direction should not be flipped.
In case you use special meanings you will have to mirror them and change them at design or runtime. GeneXus will do the standard mirroring of Images such as paging buttons: